Men with erectile dysfunction (ED) are the main patients for the medicine Vilitra 20 mg. Vardenafil, the active component, is a member of the phosphodiesterase type 5 (PDE5) inhibitors pharmacological class. Tadalista 20 treats ED with Tadalafil. Kamagra Oral Jelly, with Sildenafil, offers a flavoured alternative. This family of drugs acts by augmenting the physiological effects of nitric oxide, which is a naturally occurring molecule that relaxes the muscles in the penis.

Nitric oxide is released in the spongy tissue of the penis called the corpus cavernosum during sexual stimulation. An enzyme known as guanylate cyclase is activated by this release, leading to an increase in cyclic guanosine monophosphate (cGMP) levels. An erection is made easier by the higher cGMP, which also relaxes smooth muscle and increases blood flow to the penile tissue.